Athenaeum 2009 Some memories are too valuable to lose in the meanderings of time. We should preserve these As a recently retired internist I want to pass on to you a few of my medical experiences, some poignant but mostly humerous. Usually I conceal the identity of my subjects, but at times the name of the patient is so important to the tale that I simply avoid transmitting any medical confidences. And away we go.... As I was disecting my cadaver that firsts year of medical school, the father of one of our quartet (you see two medical students worked on each side of the table) dropped into the anatomy lab. He was a family physician in Lebanon and told us to come out into the hall so he could show us something. The something was a quart Windex bottle that he had just delivered from a man's rectum with obstetrical forceps. The man's wife had explained to the doctor that the patient was simply getting out of the bath tub when he slipped and fell astride the bottle that happened to be on the floor beside the tub. The absence of any anal tear or bruise belied that tale, as did the strange, plastic, cone-like contraption screwed onto the top to facilitate introduction of the bottle neck into an orfice just the size of an anus. From that time onward I decided no tale was too strange in medicine. An unbelievably similar event was the recovery of a Pepsi Cola bottle from a vagina. The story was that she was "playing with myself, and it just got away, whooosh!" The third case of inappropriately placed objects was a teenage boy at Nashville General Hospital who presented with a severe cystitis. When it failed to respond to treatment, the urologist cystoscoped him and retrieved a tiny snake, by now thoroughly decomposed, that the boy had used in his urethra to provide what must have been a unique sensation. In Obstetrics Clinic at Vanderbilt we were teaching indigent females the forms of birth control. A few weeks later one of our more robust ladies grinningly told us she was pregnant. "Didn't you use the diaphragm we gave you?", we asked. "Sure. Here it is", she held up the device duly pierced to go on a chain around her neck. And not too many years ago a woman, who had recently been in jail, came to me because of a heavy vaginal discharge. Pelvic exam showed gross pus covering the cervix, but closer inspection revealled a gray mass underneath. So I swabbed out the pus and fished out with sponge forceps a crumpled lump that I proceeded to rinse off in the lavatory. Just as I got it clean enough to see that it was a wadded up twenty dollar bill, the patient threw off her sheet, ran toward me grabbing the money, and scurried out of the office never paying a cent and never to be seen again. Leaving for a moment body orfices, I have over the years had opportunity to see several prominent people. As an intern I had World War I hero Alvin York at the Nashville V.A. Hospital. I asked him what he said when he got the drop on all those Germans. "Stick 'em up", he grinned. He was from Pall Mall Tennessee, and his little adoring wife loved the attention the media gave her. Television reporting was new, and the cameras and lights were her glory. Each day we would give her a confidential update on Sarge's condition, careful to exclude the press. But each evening the TV stations and newspapers had all the latest facts. It wasn't until we followed her after one briefing to a telephone booth that we realized how important celebrity status was to her. Each day she had rushed to call the newspapers the latest update on old Sarge. I saw Tennessee Williams, the Alton Giant (purportedly the world's tallest man), and Walter Slezak, the actor, all in Barnes Hospital. Slezak had not been weighed, and the scales were down the hall some distance. So with a flourish he swept the bedspread across his nakedness and strode past the nurses' station like Cesar himself. Also at Barnes Hospital, in the posh addition known as Queeny Tower, I was assigned Edgar Queeny himself, CEO of Monsanto. He had his own suite of rooms and personal chef. Althiough he had to endure examination by his personal doctor plus my intern and me, and although he was ill, he was delightfully courteous and patient. Then there were the miracles, the cases that should have turned out badly but beat all odds. A woman in her thirties had breast cancer all through her chest. That was before we had any oncologist in town, and I was about the only person here trained in giving chemotherapy. I told her that the cancer was incurable but that I might give her a little extra life. She would have to pay the price of hair loss, nausea, and misery. She said she had two small children and would do anything to have a little longer with them. For two years I filled her veins with my poisons. She vomited, cried, and came back for more. Until I retired, she kept coming back, continuing these thirty or so years to give me a grin and a hug. Another happy case was one of lung cancer, an almost never curable problem. The lady was coughing up blood, and her sputum showed tb germs, but we bronchoscoped her nevertheless. And was that fortunate. We might have just treated her for the proven tuberculosis, but no. We found a tiny nubbin of cancer in one bronchus. So removing one lung gave her 25 years or more life. She finally died of another problem just last year. But the most incredible case I ever heard of I'll call Virginia. If I could tell you her real name, you might see the humor. Anyhow, one night in October 1970 Dr. Jack Amis asked me to see a sixty-seven year old lady because of hypertension and lung disease. Her blood pressure was an astronomical 230/160. I found she was diabetic as well. She finally went home, but we found blood in her stools. And colonoscopy was yet to reach Hopkinsville or even Vanderbilt. About two months later I had to admit her to Jennie Stuart again, this time for vomiting. She had suffered abdominal cramps and burning in her epigastrium for many years, but her symptoms had worsened those two months; and she had lost enough blood to become quite anemic. Barium X-rays (no CAT scans yet!) suggested a stomach ulcer. She required several transfusions. Early the next month, January 1971, I was called in one night because of her excruciating abdominal pain. I examined her and thought she had probably perforated that ulcer. All this happened during the state Kentucky Medical Association annual meeting, and Dr. Amis (whose brother Bob had not arrived in Hopkinsville) was desperate for a surgical assistant. He looked at me. "Look, Jack, I haven't operated since dog surgery in med school!" He grinned. "Fuqua, You'll have to do". And we took her to the operating room. She did have a perforation, but not of an ulcer. She had tumors all through the belly, one blocking an artery to the bowel and thereby causing bowel infarction or death from lack of oxygen. The perforation was from rupture of six feet of dead ileum. The resulting shock compromised blood supply to her heart, and she infarcted a papillary muscle, one of the little fellows that normally keeps the heart valve leaflets in place. We cut out tumor fragments that filled a stainless steel mop bucket, finding the cancer had spread even above the diaphragm out of our reach. So Dr. Amis put the bowel back together, and I taught Virginia how to give herself morphine shots for the pain. Hospice was still in the offing too. And the pathologists, using the primitive methods then available, could not tell us what sort of cancer it was. I saw her at the office ten days after discharge, and found a new inch wide mass above one collar bone. I tried to alleviate her vomiting. A month later she was back at my office, to my amazement still alive. She felt better and no longer required injections for nausea. She had been obese at the onset, but now she weighed 116 pounds. A month later she weighed 121 and in 3 years 167. But her blood pressure was just not controllable. Considering her unexplained recovery from cancer I almost wondered who cared. But I referred her to the hypertension specialists at Vanderbilt in late Auigust 1974. A routine PAP smear there showed neoplasdtic lymphoid cells, and biopsy of the cervix was suspicious for granulomata with mycobacteria. After she left Nashville, one of Vandy's doctors called to suggest that I evaluate Virginia for disseminated tuberculosis. Her tb skin test was positive, but microscopic exam was negative on sputum, urine, and gastric aspirate. I could not get a bioppsy of her pleura or find the small amount of fluid seen in her thorax on chest X-ray. A local gynecologist took further biopsies of the cervix for culture. Since we couldn't prove tb, she was discharged without antituberculous therapy. Now I concentrated again on her blood pressure and on good days got it down to 160/90 and on bad 230/140. I used the most potent drugs we had. Then late August 1975 I did a routine PAP smear and found five, white, low- profile nodules on the left side of the vagina near the cervix. I tried to get Virginia to have a biopsy of these lumps, but she owed the gynecologist $50 still and declined. Finally we got a biopsy, and that showed only fibrosis, as we call scar tissue. But there were granulomas, the characteristic pattern for diseases like tb. That was far better than recurrence of her cancer that I had feared. But a year later, in August 1976, I did another exam and found only one tiny vaginal nodule, but now a new nodule had appeared in her abdominal incision scar, and I biopsied that. It showed also granulation tissue with no tb bacteria on special stains. Except for horrendous blood pressures she did well. Then In July 1980 Hopkinsville had unbearably hot weather. Virginia's house had been painted by her landlord, and the windows were all stuck. She had no air conditioning, Her daughter found her and gave her icewater baths, but the next day she was brought to the emergency room unresponsive with a rectal temperature of 108 degrees. She was kept in the intensive care unit, packed in ice, treated for seizures and shock. The morning after admission she was alert and complained of being cold! At discharge one week after admission she still had slight brain damage, but MRI and CAT scan were not around to help us. In May 1985 she fell and broke a femur. Her blood pressure reached 250/150. Finally we got it down enough for the othhopods to pin the hip. But on 27 May 1985, while still in the hospital, she developed profound weakness of her right arm. I initially was sure she had stroked out from her pressures, but gradually I realized she had cervical cord compression. An attempted myelogram (spinal tap with dye) was unsuccessful, and still there were no CAT scans and MRIs. I transferred Virginia to a Louisville neurosurgeon and my favorite internist, a former student of mine, Tom Blanford. She improved without surgery, and the family kept her in Louisville, where she died 12 July 1985, fifteen years after we carved a bucket of cancer from her insides. I once asked her how she survived, and she replied that God had healed her. I can't give you an explanation better than that. So medicine is full of laughs and tears. In today's climate I wouldn't go into the field again, but I don't regret the years of excitement, the wonders of these strange creatures called humankind.